THE ANTENATAL DEPRESSION IN LATE PREGNANCY

To determine the frequency of depression during the late antenatal period among women attending a tertiary care hospital for antenatal care.

  • Ayesha Nadeem DUHS
  • Shoaib Ahmed DUHS
  • Afshan Hasan DUHS
  • Sheema Mustafa DUHS
  • Fareea Mahmood DUHS
  • Mehwish Qadeer DUHS
Keywords: Antenatal Depression, Late Antenatal Period, Edinburgh Postnatal Depression Scale, Maternal Mental Health

Abstract

OBJECTIVE

To determine the frequency of depression during the late antenatal period among women attending a tertiary care hospital for antenatal care.

STUDY DESIGN

This investigation employed a descriptive cross-sectional methodology.

PLACE AND DURATION OF THE STUDY

This research was executed at the Department of Gynecology and Obstetrics at Dow University Hospital from February 17, 2025, to August 25, 2025.

METHODOLOGY

A total of 382 pregnant women aged 15–40 years in their third trimester were included, excluding those with psychiatric, neurological, or medical comorbidities. Depression was assessed using ICD-11 criteria and the Edinburgh Postnatal Depression Scale (EPDS). Participants were selected through non-probability consecutive sampling. Data was analysed in SPSS version 26.0 using descriptive statistics, chi-square, and t-tests, with significance set at p ≤ 0.05.

RESULTS

The study included 382 pregnant women in their third trimester with a mean age of 27.38 ± 7.58 years. Antenatal depression, assessed by EPDS, was present in a considerable proportion of participants. No statistically significant associations were found between depression and age (p=0.837), parity (p=0.327), marital status (p=0.665), education (p = 0.947), employment (p = 0.224), or socioeconomic status (p=0.960).

CONCLUSION

This investigation underscores that antenatal depression constitutes a considerable issue throughout the third trimester, regardless of socio-demographic attributes. The results accentuate the necessity of integrating systematic mental health assessments into antenatal care utilizing validated instruments such as the Edinburgh Postnatal Depression Scale (EPDS). Prompt identification and suitable interventions can contribute to the protection of maternal health and foster more favourable pregnancy and neonatal outcomes.

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Author Biographies

Shoaib Ahmed, DUHS

Dr A Q Khan Centre Institute of Behavioral Sciences, DUHS

Executive Director

Afshan Hasan, DUHS

Dow University Hospital

Assistant Professor (DEPARTMENT OF GYNECOLOGY AND OBSTETRICS)

Sheema Mustafa, DUHS

Dr A Q Khan Centre Institute of Behavioral Sciences, DUHS

Post Graduate Trainee (FCPS-II)

Fareea Mahmood, DUHS

Dr A Q Khan Centre Institute of Behavioral Sciences, DUHS

DESIGNATION: Post Graduate Trainee (FCPS-II)

Mehwish Qadeer, DUHS

Dr A Q Khan Centre Institute of Behavioral Sciences, DUHS

Post Graduate Trainee (FCPS-II)

References

REFERENCES

1. Biaggi A, Conroy S, Pawlby S, Pariante CM. Identifying the women at risk of antenatal anxiety and depression: A systematic review. J Affect Disord. 2016;191:62-77.

2. Miller ES, Saade GR, Simhan HN, Monk C, Haas DM, Silver RM, et al. Trajectories of antenatal depression and adverse pregnancy outcomes. Am J Obstet Gynecol. 2022;226(1):108.e1.

3. Van Niel MS, Payne JL. Perinatal depression: a review. Cleve Clin J Med. 2020;87(5):273-7.

4. Yin X, Sun N, Jiang N, Xu X, Gan Y, Zhang J et al. Prevalence and associated factors of antenatal depression: systematic reviews and meta-analyses. Clin Psychol Rev. 2021;83:101932.

5. Pajulo M, Savonlahti E, Sourander A, Helenius H, Piha J. Antenatal depression, substance dependency, and social support. J Affect Disord. 2001;65(1):9-17.

6. Becker M, Weinberger T, Chandy A, Schmukler S. Depression during pregnancy and postpartum. Curr Psychiatry Rep. 2016;18(3):32.

7. Silva-Fernandes A, Conde A, Marques M, Caparros-Gonzalez RA, Fransson E, Mesquita AR et al. Inflammatory biomarkers and perinatal depression: a systematic review. PLoS One. 2024;19(5):e0280612.

8. Phoosuwan N, Eriksson L, Lundberg PC. Antenatal depressive symptoms during late pregnancy among women in a north-eastern province of Thailand: prevalence and associated factors. Asian J Psychiatr. 2018;36:102-7.

9. Walfisch A, Sermer C, Matok I, Koren G, Einarson A. Screening for depressive symptoms. Can Fam Physician. 2011;57(7):777-778.

10. Tanuma-Takahashi A, Tanemoto T, Nagata C, Yokomizo R, Konishi A, Takehara K et al. Antenatal screening timeline and cutoff scores of the Edinburgh Postnatal Depression Scale for predicting postpartum depressive symptoms in healthy women: a prospective cohort study. BMC Pregnancy Childbirth. 2022;22(1):527.

11. Howard LM, Molyneaux E, Dennis CL, Rochat T, Stein A, Milgrom J. Non-psychotic mental disorders in the perinatal period. Lancet. 2014;384(9956):1775-88.

12. Stein A, Pearson RM, Goodman SH, Rapa E, Rahman A, McCallum M, et al. Effects of perinatal mental disorders on the fetus and child. Lancet. 2014;384(9956):1800-19.

13. World Health Organization. Integrating perinatal mental health into maternal and child health services: WHO recommendations. Geneva: WHO; 2022.

14. Gavin NI, Gaynes BN, Lohr KN, Meltzer-Brody S, Gartlehner G, Swinson T. Perinatal depression: a systematic review of prevalence and incidence. Obstet Gynecol. 2005;106(5 Pt 1):1071-83.

15. Woody CA, Ferrari AJ, Siskind DJ, Whiteford HA, Harris MG. A systematic review and meta-regression of the prevalence and incidence of perinatal depression. J Affect Disord. 2017;219:86-92.

16. O’Connor E, Rossom RC, Henninger M, Groom HC, Burda BU. Primary care screening for and treatment of depression in pregnant and postpartum women: evidence report and systematic review for the US Preventive Services Task Force. JAMA. 2016;315(4):388–406.

17. Fisher J, Mello MC, Patel V, Rahman A, Tran T, Holton S, et al. Prevalence and determinants of common perinatal mental disorders in women in low- and lower-middle-income countries: a systematic review. Bull World Health Organ. 2012;90:139-49.

18. Norhayati MN, Hazlina NH, Asrenee AR, Emilin WM. Magnitude and risk factors for postpartum symptoms: a literature review. J Affect Disord. 2015;175:34–52.
Published
2026-06-27
How to Cite
1.
Ayesha Nadeem, Shoaib Ahmed, Afshan Hasan, Sheema Mustafa, Fareea Mahmood, Mehwish Qadeer. THE ANTENATAL DEPRESSION IN LATE PREGNANCY: To determine the frequency of depression during the late antenatal period among women attending a tertiary care hospital for antenatal care. . J Pak Psychiatr Soc [Internet]. 2026Jun.27 [cited 2026Jun.29];23(02). Available from: https://jpps.pk/index.php/journal/article/view/1194