ASSOCIATION OF LIPID PROFILE WITH DEPRESSIVE FEATURES IN YOUNG HYPERTENSIVES

  • Ravi Gupta Department of Psychiatry, SMS Medical College, JLN Marg, Jaipur, India.
  • Ram Kumar Solanki Department of Psychiatry, SMS Medical College, JLN Marg, Jaipur, India.
  • Vaibhav Dubey Department of Psychiatry, SMS Medical College, JLN Marg, Jaipur, India.
  • Purav Kumar Midha Department of Psychiatry, SMS Medical College, JLN Marg, Jaipur, India.
  • Vijay Pathak Department of Cardiology, SMS Medical College, JLN Marg, Jaipur, India.

Abstract

Objectives: To find out

(a) the correlation of various components of serum lipids with depression score; (b) whether severity of depression differ between the people with normal serum lipids & dyslipidemia;and (c) whether the lipid components differ between depressed and non-depressed people.
Design: Cross Sectional Cohort study.
Place and duration of the study: This study was conducted at Sawai Man Singh Medical College and
Hospital, Jaipur, India from January 2001 to June 2002.
Subjects and Methods: 100 young primary hypertensive subjects were included in this study. Their fasting blood lipid profile was ascertained and their depressive feelings were rated with the help of HAM-D.
Results: In this study, total lipids, high density lipoprotein, low density lipoprotein, very low density lipoproteins and triglycerides were positively correlated with the HAM D score. Depressed subjects (HAMD>17) had higher levels of total lipids (P=0.002), HDL (P=0.04), VLDL (P=0.02) and TG (P=0.001). Similarly subjects with higher cholesterol levels (P=0.05), normal HDL (P=0.003), normal LDL (P<0.001); higher VLDL (P=0.002) and higher TGs (P<0.001) had higher scores on HAM-D.
Conclusions: This study suggests that low HDL, high LDL protects from the depression. On the other hand, high cholesterol, VLDL and TG increase the risk of depression.

Key words: Hypertension, Young, Lipid profile, Depressive features.

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Published
2008-12-31
How to Cite
1.
Gupta R, Solanki RK, Dubey V, Midha PK, Pathak V. ASSOCIATION OF LIPID PROFILE WITH DEPRESSIVE FEATURES IN YOUNG HYPERTENSIVES. J Pak Psychiatr Soc [Internet]. 2008Dec.31 [cited 2024Sep.19];5(2):101-4. Available from: https://jpps.pk/index.php/journal/article/view/724
Issue
Vol 5 No 2 (2008): Journal of Pakistan Psychiatric Society
Section
Original Article

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